Ayurveda perspective and management of intrahepatic cholestasis during pregnancy - Dr. Anjali Verma
Abstract: Intrahepatic cholestasis of pregnancy (ICP) is a commonest pregnancy-specific liver disorder characterized by pruritus in the third trimester, elevated serum bile acids and associated with increased risk of adverse fetal outcomes. In Ayurveda, ICP has a close manifestation with Garbha Peedan Janya Vyadhi, Pitta vitiation characterized by Kandu i.e. pruritus in 7th month of pregnancy. Pitta vitiation due to Garbha Peedan can be consider as cholestasis due to increasing amount of estrogen, progesterone in third trimester and mechanical pressure exerts by growing fetus on biliary drainage. Liver is consider as seat of Pitta, thus liver preparations with Pitta Shamaka and Pitta virechak properties potently break the etio-pathogenesis of ICP by channelize the flow of bile. Clinical Evidences in support of above analysis are also proved that liver preparation played a significant role in management of ICP.